If you have troubles since the update to WordPress 4.5 please read this post before opening a new thread.
Please try to flush the permalinks (go to Settings > Permalinks and hit the save button). If this doesn’t solve the issue install: http://wordpress.org/plugins/rewrite-rules-inspector/ and click the “Flush rules” button on the right side. If this still doesn’t help you maybe need to update your htaccess file manually: http://codex.wordpress.org/Using_Permalinks#Creating_and_editing_.28.htaccess.29
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